phosphatase ester hydrolysis

By Targets:	Phosphatase (3) Antibiotic (3) Apoptosis (1) Bacterial (3) Biochemical Assay Reagents (1) Endogenous Metabolite (1) Parasite (3)
By Research Areas:	Cancer (2) Infection (3) Metabolic Disease (1)

Targets Recommended: Phosphatase CETP PTEN SHP2

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1064

Clindamycin phosphate 2 Publications Verification Clindamycin 2-phosphate; U-28508	Bacterial Antibiotic Parasite	Infection
Clindamycin phosphate (Clindamycin 2-phosphate) is a broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin phosphate is the proagent of Clindamycin (HY-B1455) with no antimicrobial activity in vitro but can be rapidly converted in vivo to the active parent agent, Clindamycin, by phosphatase ester hydrolysis. Clindamycin phosphate can be used for researching acne and bacterial vaginosis .Clindamycin phosphate has no cytotoxicity。 Combined with platelet rich fibrin (PRF), PRF-Clindamycin phosphate enhances antimicrobial properties .

HY-P2818

Alkaline phosphatase, Bovine intestine 1 Publications Verification Apase	Endogenous Metabolite	Metabolic Disease Cancer
Alkaline phosphatase, Bovine intestine (Apase) is a membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase can be used in molecular biology and enzyme-free analysis. Inhibition of tissue nonspecific alkaline phosphatase can block intracellular lipid accumulation .

HY-120166

DiFMUP 6,8-Difluoro-4-methylumbelliferyl phosphate	Phosphatase	Others
DiFMUP is a fluorogenic substrate, and has been widely used for the continuous detection of phosphatase activities. DiFMUP is hydrolysis by a phosphatase results in the release of Xuorescent DIFMU, which can be easily followed in continuous mode by a Xuorescence reader .

HY-B1064A

Clindamycin phosphate hydrochloride Clindamycin 2-phosphate hydrochloride; U-28508 hydrochloride	Bacterial Antibiotic Parasite	Infection
Clindamycin phosphate (Clindamycin 2-phosphate) hydrochloride is a broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin phosphate hydrochloride is the proagent of Clindamycin (HY-B1455) with no antimicrobial activity in vitro but can be rapidly converted in vivo to the active parent agent, Clindamycin, by phosphatase ester hydrolysis. Clindamycin phosphate hydrochloride can be used for researching acne and bacterial vaginosis .

HY-D1676

Thymolphthalein monophosphate disodium hydrate	Phosphatase	Others
Thymolphthalein monophosphate disodium hydrate is a chromogenic substrate for the determination of acid phosphatase and alkaline phosphatase. Thymolphthalein is released during the reaction, increases the pH of the medium for easy detection, produces color and stops hydrolysis. Thymolphthalein monophosphate disodium hydrate can be used for the specific detection of prostatic phosphatase in serum .

HY-137135A

Cantharidic acid disodium	Phosphatase Apoptosis	Cancer
Cantharidic acid disodium is the hydrolysis product of the acid anhydride Cantharidin that induces apoptosis in various human cancer cells. Cantharidic acid disodium is a selective *protein phosphatase* 2 (PP2A) and PP1** inhibitor withIC₅₀ values of 50 nM and 600 nM, respectively .

HY-116022A

4-Nitrophenyl phosphate disodium hexahydrate 2 Publications Verification p-Nitrophenyl phosphate disodium hexahydrate	Biochemical Assay Reagents	Others
4-Nitrophenyl phosphate (p-nitrophenyl phosphate) disodium hexahydrate is widely used as a small molecule phosphotyrosine-like substrate in activity assays for protein tyrosine phosphatases. 4-Nitrophenyl phosphate disodium hexahydrate is a colorless substrate that upon hydrolysis is converted to a yellow 4-nitrophenolate ion that can be monitored by absorbance at 405 nm .

HY-B1064R

Clindamycin phosphate (Standard) Clindamycin 2-phosphate (Standard); U-28508 (Standard)	Bacterial Antibiotic Parasite	Infection
Clindamycin phosphate (Standard) is the analytical standard of Clindamycin phosphate. This product is intended for research and analytical applications. Clindamycin phosphate (Clindamycin 2-phosphate) is a broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin phosphate is the proagent of Clindamycin (HY-B1455) with no antimicrobial activity in vitro but can be rapidly converted in vivo to the active parent agent, Clindamycin, by phosphatase ester hydrolysis. Clindamycin phosphate can be used for researching acne and bacterial vaginosis .

Cat. No.	Product Name	Type

HY-D1676

Thymolphthalein monophosphate disodium hydrate	Fluorescent Dyes/Probes
Thymolphthalein monophosphate disodium hydrate is a chromogenic substrate for the determination of acid phosphatase and alkaline phosphatase. Thymolphthalein is released during the reaction, increases the pH of the medium for easy detection, produces color and stops hydrolysis. Thymolphthalein monophosphate disodium hydrate can be used for the specific detection of prostatic phosphatase in serum .

Thymolphthalein monophosphate disodium hydrate

Fluorescent Dyes/Probes

Thymolphthalein monophosphate disodium hydrate is a chromogenic substrate for the determination of acid phosphatase and alkaline phosphatase. Thymolphthalein is released during the reaction, increases the pH of the medium for easy detection, produces color and stops hydrolysis. Thymolphthalein monophosphate disodium hydrate can be used for the specific detection of prostatic phosphatase in serum .

Cat. No.	Product Name	Type

HY-116022A

4-Nitrophenyl phosphate disodium hexahydrate 2 Publications Verification p-Nitrophenyl phosphate disodium hexahydrate	Biochemical Assay Reagents
4-Nitrophenyl phosphate (p-nitrophenyl phosphate) disodium hexahydrate is widely used as a small molecule phosphotyrosine-like substrate in activity assays for protein tyrosine phosphatases. 4-Nitrophenyl phosphate disodium hexahydrate is a colorless substrate that upon hydrolysis is converted to a yellow 4-nitrophenolate ion that can be monitored by absorbance at 405 nm .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-P2818

Alkaline phosphatase, Bovine intestine 1 Publications Verification Apase	Structural Classification Natural Products Animals Classification of Application Fields Source classification Metabolic Disease Disease Research Fields	Endogenous Metabolite
Alkaline phosphatase, Bovine intestine (Apase) is a membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase can be used in molecular biology and enzyme-free analysis. Inhibition of tissue nonspecific alkaline phosphatase can block intracellular lipid accumulation .

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